Remember disable your antivirus software : gameplay tool is using memory hack module
and some AV soft missunderstand it with virus, but believe me it's not the virus.
For upgrade to new version you must delete all files & folder from old version (for remove all old effort)
+ Gameplay tool - run.exe
+ Gameplay tool - config.exe
+ Gameplayjen
Extract & Copy all files to PES2011 installed foder
Run "Gameplay tool - config.exe" for configuration
Save config (If you feel gameplay is not changed ingame, try run config & save again)